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Niles Pierce : ウィキペディア英語版
Niles Pierce

Niles A. Pierce is an American mathematician, bioengineer, and professor at the California Institute of Technology. He is a leading researcher in the fields of DNA computing and DNA nanotechnology. His research is focused on kinetically controlled DNA and RNA self-assembly. Pierce is working on applications in bioimaging.
Pierce graduated from Princeton University in 1993 with a BSE in Mechanical & Aerospace Engineering. He attended Oxford University as a Rhodes Scholar, completing a DPhil in Applied Mathematics in 1997. He joined the faculty of the California Institute of Technology in 2000.
==Works==

* ''Next-generation in situ hybridization chain reaction: higher gain, lower cost, greater durability'' H.M.T. Choi, V.A. Beck, and N.A. Pierce (ACS Nano ) 8(5):4284-4294, 2014.
* ''Conditional Dicer substrate formation via shape and sequence transduction with small conditional RNAs'' L.M. Hochrein, M. Schwarzkopf, M. Shahgholi, P. Yin, and N.A. Pierce (J Am Chem Soc ) 135(46):17322-17330, 2013.
* ''Nucleic acid sequence design via efficient ensemble defect optimization'' J.N. Zadeh, B.R. Wolfe, and N.A. Pierce (J Comput Chem ) 32:439-452, 2011.
* ''NUPACK: Analysis and design of nucleic acid systems'' J.N. Zadeh, C.D. Steenberg, J.S. Bois, B.R. Wolfe, M.B. Pierce, A.R. Khan, R.M. Dirks, and N.A. Pierce (J Comput Chem ) 32:170-173, 2011.
* ''Programmable in situ amplification for multiplexed imaging of mRNA expression'' H.M.T. Choi, J.Y. Chang, L.A. Trinh, J.E. Padilla, S.E. Fraser, and N.A. Pierce (Nature Biotechnol ) 28:1208-1212, 2010.
* ''Programming biomolecular self-assembly pathways'' P. Yin, H.M.T. Choi, C.R. Calvert, and N.A. Pierce (Nature ) 451:318-322, 2008.
* ''Thermodynamic analysis of interacting nucleic acid strands'' R.M. Dirks, J.S. Bois, J.M. Schaeffer, E. Winfree, and N.A. Pierce (SIAM Rev ) 49(1):65-88, 2007.
* ''Triggered amplification by hybridization chain reaction'' R.M. Dirks and N.A. Pierce (Proc Natl Acad Sci USA ) 101(43):15275-15278, 2004.
* ''A synthetic DNA walker for molecular transport'' J.-S. Shin and N.A. Pierce (J Am Chem Soc ) 126:10834-10835, 2004.

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